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尹建华
姓名: 尹建华 性别: 职务:
职称: 教授 导师类别: 博士生导师 办公室:
研究领域:
电话: Email: yin at nuaa.edu.cn
个人简介

南京航空航天大学生物医学工程系教授,中国光学学会生物医学光子学专业委员会委员,多个学会会员。发表文章七十余篇,一作及通讯作者SCI论文三十多篇。主持NSFC面上项目、教育部博士学科点基金、江苏省自然科学基金和江苏省“六大人才高峰”高层次人才计划等项目。作为项目主要完成人参与完成2项美国NIH R01项目,2项日本文部省重大项目,3项国家自然科学基金面上项目。

目前从事的主要研究领域包括:

生物医学光谱学及成像(Biomed Spectroscopy and Micro-Imaging)

生医光子学技术开发及应用 (D&A of Biomed Photonics Tech.)

光谱及其图像分析(Spectroscopic Image Analysis)

界面生物分析化学(Bioanalytical Chem @interface )

学术成果

部分代表性成果:[to update soon or to visit http://bmsi.nuaa.edu.cn/]

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【红外光谱成像&化学计量学&光谱分析&荧光成像光谱@软骨与骨关节炎】

[1] Zhi-Hua Mao, Jian-Hua Yin*, Xue-Xi Zhang, Xiao Wang, Yang Xia, Discrimination of healthy and osteoarthritic articular cartilage by Fourier transform infrared imaging and Fisher’s discriminant analysis, Biomed. Opt. Express, 7(2) 448-453, 2016(SCI IF3.648)

[2] Zhi-Hua Mao †, Yue-Chao Wu †, Xue-Xi Zhang, Hao Gao and Jian-Hua Yin*, Comparative study on identication of healthy and osteoarthritic articular cartilages by fourier transform infrared imaging and chemometrics methods, J Innov Opt Health Sci, 10, 1650054, 2017 (SCI)

[3] Xue-Xi Zhang, Jian-Hua Yin*, Zhi-Hua Mao, Yang Xia, Discrimination of healthy and osteoarthritic articular cartilages by Fourier transform infrared imaging and partial least squares-discriminant analysis, J Biomed Opt, 20(6), 060501, 2015(SCI IF2.85)

[4] Xue-Xi Zhang, Zhi-Hua Mao, Jian-Hua Yin*, Yang Xia, Determination of collagen and proteoglycan concentration in osteoarthritic and healthy articular cartilage by Fourier transform infrared imaging and partial least square, Vib Spectrosc., 78, 49-53, 2015(SCI IF2.1)

[5] Zhi-Hua MAO, Xue-Xi ZHANG, Yue-Chao WU, Jian-Hua YIN*, XIA Yang, Fourier Transform Infrared Microscopic Imaging and Fisher Discriminant Analysis for Identification of Healthy and Degenerated Articular Cartilage, Chin J Anal Chem, 43, 518-522, 2015(SCI)(EN)

毛之华, 张学喜, 吴曰超,尹建华*,Xia Yang, 健康和病变关节软骨的傅里叶变换红外光谱显微成像及Fisher判别. 分析化学, 43: 518-522, 2015 (SCI) (CN)

[6] Jian-Hua Yin, Yang Xia*, "Proteoglycan Concentrations in Healthy and Diseased Articular Cartilage by Fourier Transform Infrared Imaging and Principal Component Regression", Spectrochim Acta A: Molecular and Biomolecular Spectroscopy, 133, 825-830, 2014 (SCI, IF=2.653)

[7] Xue-Xi Zhang, Zhi-Yan Xiao, Jian-Hua Yin*, et al. Concentration Determination of Collagen and Proteoglycan in Bovine Nasal Cartilage by Fourier Transform Infrared Imaging and PLS, Proc. of SPIE, 9230: 923015-1~7, 2014 (EI)

[8] 吴曰超, 张学喜, 毛之华, 尹建华*. 关节软骨内胶原纤维各向异性的红外光谱学显微成像研究, 光谱学与光谱分析, 36(7): 2071-2075, 2016 (SCI)

[9] 尹建华*,黄凤玲,钱志余,谢捷如,傅里叶变换红外光谱学显微成像技术在骨病研究中的应用和进展,光谱学与光谱分析, 34, 340-343, 2014 (SCI)

[10] 王潇,吴曰超,何俊豪,毛之华,张学喜,蔡金洋,王强,尹建华*, 关节软骨的荧光显微检测方法研究, 光散射学报, 28(2), 185-189, 2016

[11] 毛之华,尹建华*, 基于主成分分析的不同预处理方法对关节软骨分类的影响, 光散射学报, 28(3), 264-269, 2016

[12] 吴曰超, 尹建华*, 刘玉, 毛之华, 关节软骨红外光谱成像及分析方法研究,南京航空航天大学学报, 47, 421-427, 2015 (EI)

[13] 尹建华,关节软骨和骨关节炎的傅里叶变换红外光谱学显微成像研究进展,科学通报, 59 (27) ,2645 – 2651, 2014 (重核)

[14] 尹建华,关节软骨主成分的红外光谱学分析及表征,光散射学报,26(2),213-218, 2014

[15] 尚林伟,尹建华*,软骨退变的显微荧光光谱研究,中国科技论文,11(24),2811-2815,2016

[16] Z. Xiao, J.H. Yin*, “Spectroscopic studies on bilirubin aggregate at liquid/liquid interface”, Anal. Bioanal. Chem., 405, 2723-2728, 2013 (SCI, IF=3.778)

[17] J.H. Yin*, Y. Xia, “Comparison of macromolecular component distributions in osteoarthritic and healthy cartilages by Fourier transform infrared imaging”, J Innov. Opt. Health Sci., 6, 1350048, 2013 (SCI)

[18] J.H. YIN, Y. Xia*, “Concentration Profiles of Collagen and Proteoglycan in Articular Cartilage by Fourier Transform Infrared Imaging and Principal Component Regression”, Spectrochim. Acta A, 88, 90-96, 2012 (SCI, IF=2.663)

[19] J.H. YIN, Y. Xia*, “Chemical Visualization of Individual Chondrocytes in Articular Cartilage by Attenuated-Total-Reflection Fourier Transform Infrared Microimaging”, Biomed. Opt. Express, 2, 937-945, 2011 (SCI, IF=3.648)

[20] J.H. YIN, Y. Xia*, “Depth-dependent Anisotropy of Proteoglycan in Articular Cartilage by Fourier Transform Infrared Imaging”, Vib. Spectrosc., 57, 338-341, 2011 (SCI, IF=2.083)

[21] J.H. YIN, Y. Xia*, “Macromolecular Concentrations in Bovine Nasal Cartilage by Fourier Transform Infrared Imaging and Principal Component Regression”, Appl. Spectrosc., 64, 1199-1208, 2010 (SCI, IF=1.663)

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【共焦显微拉曼&圆二色谱&荧光光谱@界面分子聚集】

[22] J.H. Yin, H. Watarai*, “Effect of Chloroform on Complexation and Chiral Aggregation of Bilirubin–Bovine Serum Albumin at Heptane/Water Interface”, J. Colloid Interface Sci., 329, 325-330, 2009 (SCI, IF=3.263)

[23] D. Tokunaga, H. Takechi, J.H. Yin, H. Watarai*, T. Ohde, “Microscopic Observation of Second Harmonic Generation from Chiral Surfaces”, Anal. Sci., 25, 311-314, 2009 (SCI, IF=1.255)

[24] J.H. Yin, H. Watarai*, “Chiral Complexation and Aggregation of Bilirubin with Serum Albumin at Liquid/Liquid Interface”, Anal. Bioanal. Chem., 389, 895-902, 2007 (SCI, IF=3.778)

[25] J.H. Yin, H. Watarai*, “Resonance Raman Spectroscopic Study on Chiral Aggregation of Bilirubin-Bovine Serum Albumin Complex Formed at Liquid/Liquid Interface”, Anal. Sci., 23 841-846, 2007 (SCI, IF=1.255)

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【光纤Raman光谱学】

[26] J.H. Yin*, Z.Y. Xiao, Z.W. Li, “Ultralow concentration beta-carotene molecule detection by liquid-core optical fiber resonance Raman spectroscopy”, Vib. Spectrosc., 62, 7-9, 2012 (SCI, IF=2.083)

[27] J.H. Yin, Z.W. Li*, “Resonance Raman Spectra of n-pi* Singlet–triplet Transition of p- benzoquinone at Low Concentrations”, Spectrochim. Acta Part A, 61, 495–498, 2005 (SCI, IF=2.098)

[28] J.H. Yin, Z.W. Li*, Y.J. Tian, Z.W. Sun, X.L. Song, “A Study on Raman Scattering Cross Section of Carbon Tetrachloride at low Concentrations”, Appl. Phys. B: Lasers and Optics, 80, 573-576, 2005 (SCI, IF=2.189)

[29] J.H. Yin, Z.W. Li*, C.N. Ren, L.Y. Zhang, “Visible Absorption Spectra of n-pi* Singlet-Triplet Transition of p-benzoquinone in CS2 and its Resonance Raman Spectra”, Spectrosc. Spect. Anal., 25, 1821-1823, 2005 (SCI)

[30] J.H. Yin, S.Q. Gao, Z.W. Li*, Y.N. Yu, G.H. Lu, Y.J. Tian, “Effect of Solution Concentration on Raman Scattering Cross Section of Carbon Tetrachloride”, J. Raman Spectrosc., 35, 1042-1046, 2004 (SCI, IF=3.087)

[31] J.H. Yin, S.Q. Gao, X.F. Xu, Z.W. Li*, “Experimental Studies on Effect of Concentration of CS2 on Linewidth and Frequency Shift of Raman Spectrum”, Chem. J. Chin. Univ., 23, 2300- 2302, 2002 (SCI)

承担项目

主持项目:

1. 2016 江苏省第十三批“六大人才高峰”高层次人才计划项目

2. 国家自然科学基金面上项目 ( 61378087)

3. 高等学校博士学科点专项科研基金 (20133218120017)

4. 江苏省自然基金 (BK20151478)

5. 南京航空航天大学引进人才启动基金 (1003-56YAH13005)

参研项目:

2 项美国NIH R01项目 2008-2011

2 项日本文部省重大项目 2005-2008

3 项国家自然科学基金 2000-2005

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